Anjelica L. Gonzalez is Associate Professor of Biomedical Engineering. Her appointment in Biomedical Engineering, in association with the Vascular Biology and Therapeutics Program, has provided a supportive and convenient platform for her research, focused on the development of biomaterials for use as investigational tools, particularly for the investigation of immunological responses to inflammatory signals from endogenous and exogenous sources.
Gonzalez has a dedicated interest in training the next generation of scientists to think with an interdisciplinary approach to problems and to have a scientifically global perspective. The Gonzalez lab combines organic chemistry, molecular biology, mathematics, computational modeling and image analysis to develop human tissue-based biomimetic scaffolds to better understand healthy and diseased states.
Research projects in the Gonzalez lab include the development of biomaterials for investigating the influence of outside-in mediated signaling through adhesion molecules on cellular architecture and subsequent signaling pathways. These activities are investigated in leukocytes, neural stem cells, pericytes and endothelial cells. Research areas include microvascular and tissue homeostasis of lung, skin, and brain. This work extends to many different diseases and disorders including wound repair, scar formation, fibrosis, and stroke.