Publications

2021

  • Matta, R., Yousafzai, MS., Murrell, M., Gonzalez, AL. Endothelial cell secreted metalloproteinase-2 enhances neural stem cell N-cadherin expression, clustering, and migration. The FASEB journal. 2021; 35:e21311. https://doi.org/10.1096/fj.202002302
    org/10.1096/fj.20200 2302RR
  • Gonzalez Porras, MA., Stojkova, K., Vaicik, MK., Pellowe, A., Goddi, A., Carmona, A., Long, B., Qutub, AA., Gonzalez, AL., Chohen, RN., Brey, EM. Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity. Sci Rep 11, 5442 (2021). https://doi.org/10.1038/s41598-021-84828-z
     

2020

  • Ghuman, H., Matta, R., Tompkins, A., Nitzche, F., Badylak, S.F., Gonzalez, A.L., Modo, M. ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke. Brain Research Bulletin. 2020. 168;120-137. https://doi.org/10.1016/j.brainresbull.2020.12.004

2019

  • Matta, R., Gonzalez, AL. Engineered Biomimetic Neural Stem Cell Niche. Curr Stem Cell Rep 5, 109–114 (2019). https://doi.org/10.1007/s40778-019-00161-2

  • Pellowe AS, Sauler M, Hou Y, Merola J, Liu R, Calderon B, Lauridsen HM, Harris MR, Leng L, Zhang Y, Tilstam PV, Pober JS, Bucala R, Lee PJ , and Gonzalez AL. Endothelial cell-secreted MIF reduces pericyte contractility and enhances neutrophil extravasation. FASEB J. 2019. Feb;33(2):2171-2186 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338650/

  • Matta, R., Lee, S., Genet, N., Hirschi, K., Thomas JL., and Gonzalez AL. Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone. Sci Rep 9, 17798. 2019 doi:10.1038/s41598-019-54167-1 https://www.nature.com/articles/s41598-019-54167-1
     
  • Korde A, Ahangari F, Haslip M, Zhang X, Liu Q, Chn L, Gomez-Villalobos J, Chupp G, Pober J, Gonzalez AL, Takyar S. An endothelial microRNA-1 regulated network controls eosinophil trafficking in asthma and chronic rhinosinusitis. Accepted Journal of Allergy and Clinical Immunology, Oct. 2019 https://www.ncbi.nlm.nih.gov/pubmed/32035607

2018

  • Matta R, Gonzalez AL. Stroke Repair via Biomimicry of the Subventricular Zone. Frontiers in Materials. doi: 10.3389/fmas.2018.00015

2017

  • Sava P, Ramanathan A, Dobronyi A, Peng X, Sun Y,  Ledesma-Mendoza A, Herzog EL, Gonzalez AL. Human Pericytes Adopt Myofibroblast Properties in the Microenvironment of the  Human IPF Lung. Journal of Clinical Investigation Insight. doi: 10.1172/jci.insight.96352
     
  • Pellowe A, Lauridsen H, Matta R, Gonzalez AL. Ultrathin porated elastic hydrogels as a biomimetic basement membrane for dual cell culture. Journal of Visual Experimentation. doi: 10.3791/56384
     
  • Lauridsen HM*, Pellowe A*, Ramanathan A, Liu R, Miller-Jensen K, McNiff JM, Pober JS, Gonzalez AL. TNFα and IL-17A-activation induces pericyte-mediated basement membrane remodeling in human neutrophilic dermatoses. American Journal of Pathology. Jun 10. doi: 10.1016/j.ajpath.2017.04.008. 
     
  • Lauridsen HM, Gonzalez AL. Biomimetic, ultrathin and elastic hydrogels regulate human neutrophil extravasation across endothelial-pericyte bilayers. PLoS One 12(2): e0171386. doi:10.1371/journal.pone.0171386.

2016

  • Ryu C, Sun H, Gulati M, Herazo-Maya JD, Chen Y, Osafo-Addo A, Brandsdorfer C, Winkler J, Blaul C, Faunce J, Pan H, Woolard T, Tzouvelekis A, Antin-Ozerkis DE, Puchalski JT, Wu T, Slade M, Gonzalez AL, Bogenhagen DF, Kirillov V, Feghali-Bostwick C, Gibson K, Lindell K, Shadel G, Herzog RI, Dela Cruz C, Mehal W, Kaminski N, Herzog E, and Trujillo G. Extracellular Mitochondrial DNA is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine Aug 7. doi: 10.1164/rccm.201612-2480OC.
     
  • Liu R, Lauridsen HM, Amezquita RA, Pierce RW, Jane-wit D, Fang C, Pellowe AS, Kirkles-Smith NC, Gonzalez AL, Pober JS. IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium. The Journal of Immunology. 197:2400-2408
     
  • Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL. Netrin-1 regulates fibrocyte accumulation in the decellularized fibrotic scleroderma lung microenvironment and in bleomycin induced pulmonary fibrosis. Arthritis & Rheumatology. doi: 10.1002/art.3957

2015

  • Brown L, Sava P, Garcia C, Gonzalez AL. Proteomic Analysis of Pericyte Derived Extracellular Matrix. Cellular and Molecular Bioengineering; 8(3): 349-363. 2015.**Selected for Young Innovator Issue
     
  • Pellowe A a​nd Gonzalez AL. The Extracellular Matrix, Biomimicry and Creation of Advanced Biomaterial Devices. WIREs Nanomedicine and Nanobiotechnology; doi: 10.1002/wnan.1349. 
     

  • Sava P, Cook IO, Mahal R, Gonzalez AL.  Fibronectin-Rich Pericyte Deposited Microvascular Matrix Increases Leukocyte Recruitment in Bleomycin Induced Fibrosis.  Microcirculation. 22(1): 54-67. 

2014

  • Kim HY, Skokos ES, Meyer DJ, Agaba P, Gonzalez AL. αVβ3 Integrin Regulation of Respiratory Burst in Fibrinogen Adherent Human Neutrophils. Cellular and Molecular Bioengineering. 7(2): 231-242. 2014. doi: 10.1007/s12195-014-0322-2

  • Laurdisen HM*, Walker BJ*, Gonzalez AL. Chemically- & mechanically tunable porated polyethylene glycol gels for integrin dependent and independent leukocyte chemotaxis. Technology. 2(2):133-143. 2014. doi:10.1142/S2339547814500113

  • Gonzalez AL, Berger CE, Remington J, Girardi M, Tigelaar RE, Edelson, R. Integrin Driven Monocyte to Dendritic Cell Conversion in Modified Extracorporeal Photochemotherapy. Clinical & Experimental Immunology. 175(3):449-457. 2014. PMID: 24188174

  • Lauridsen H, Pober JS, Gonzalez AL. A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment. The FASEB Journal. 28(3):1166-1180. 2014. PMID: 24297702**featured in Yale Scientific

​2013

  • Pu KM, Sava P and AL Gonzalez.  Microvascular Targets in Fibrosis. Yale Journal of Biology and Medicine. 86(4):537-554. 2013. PMCID: 24348218

  • Ayres-Sander CE, Lauridsen H, Maier CL, Sava P, Pober JS, Gonzalez AL. Transendothelial Migration Enables Subsequent Transmigration of Neutrophils through Underlying Pericytes. PLoS One. 8(3):e60025. 2013. PMCID: PMC3608600 **as of June 2017 among top 25% most cited PLoS One articles.

2012

  • Huang RB, Gonzalez AL and Eniola-Adefeso E.  Laminar Shear Stress Elicit Distinct Endothelial Cell E-Selectin Expression Induced via TNFα and IL-1β.  Biotechnology and Bioengineering. 110(3): 99-1003. 2012. PMID: 23055258
     
  • Lee SW, Kim GS, Wu Y, Kim DJ, Lu Y, Kwak M, Han L, Hyung JW, Seol JK, Sander C, Gonzalez AL, Li J, and Fan R.  Nanowire Substrate-Based Laser Scanning Cytometry for Quantitation of Circulating Tumor Cells.  Nano Letters. 12(6): 2697−2704. 2012. PMCID: PMC3381426
     
  • ​Padmanabhan J and Gonzalez AL.   Investigation Of The Effects Of Extracellular Matrix Proteins On Neutrophil-Endothelial Interaction – A Roadway To Multiple Therapeutic Opportunities. Yale Journal of Biology and Medicine. 85(2):167-85. 2012. PMCID: PMC3375712
     
  • ​Katz DL, Green LW, Murimi M, Gonzalez AL, Njike VY.  The multisite translational community trial & community based participatory research:  A failure to communicate?  American Journal of Public Health. 102(4):581-2. 2012. PMCID: PMC3489354

​2011

  • Ayers-Sander CE and Gonzalez AL.  Approaches in extracellular matrix engineering for determination of adhesion molecule mediated single cell function.  Frontiers in Biology. 8(1): 32-49. 2011. DOI: 10.1007/s11515-012-1199-x
     
  • ​Katz DL, Murimi M, Gonzalez AL, Njike V, Green LW.  From controlled trial to community adoption: The multisite translational community trial. American Journal of Public Health.  101(8):e17-27. 2011. PMID: 21680935

​2010-2004

  • Njike V, Faridi Z, Dutta S, Gonzalez-Simon AL, and Katz DL. Daily egg consumption in hyperlipidemic adults -Effects on endothelial function and cardiovascular risk.  Nutrition Journal. 9(28): 1-9. 2010. PMID: 20598142
     
  • Gonzalez, AL, El-Bjeirami W, West JL, McIntire LV, Smith CW. Transendothelial migration enhances integrin dependent human neutrophil chemokinesis. Journal of Leukocyte Biology. 81(3): 686-95. 2007. PMID: 17164427
     

  • Gonzalez, AL, A.S. Gobin, J.L. West, L.V. McIntire, C.W. Smith.  Integrin Interactions with immobilized peptides in polyethylene glycol diacrylate hydrogels.  Tissue Engineering.  10(11-12): 1775-1786. 2004. PMID: 15684686